AND rHAEMACOFOEIA. 541 



profusely, and then it should be dlscontumed a short time. 

 Whenever sublimate makes a horse sick, or causes any uneasi- 

 ness in the bowels, it should be immediately discontinued. In 

 the various experiments that have been made upon glandered 

 horses, it has been given in very large doses, even to the extent 

 of two drachms twice a day. Xo good, however, has ever re- 

 sulted from such large doses, and the ]ioor animals have often 

 been dreadfully tortured by them. I am now decidedly of 

 opinion, that in glanders and farcy the milder preparations 

 should be preferred, especially Ethio[)s mineral, and the mercu- 

 rial or blue pill. INI. Dupuy injected a solution of sublimate 

 into the jugular vein of a glandered horse. It caused almost 

 immediately severe colic pains, and a continual shaking of the 

 tail. It produced also a remarkable effect upon the kidneys, 

 causing the horse to stale frequently, even twelve times in the 

 space of a quarter of an hour. The following day he injected a 

 stronger solution, which caused still more distressing symptoms ; 

 the next day a still stronger solution, which, after tormenting 

 the poor animal for some time, put an end to his sufferings. 

 The symptoms of glanders were not at all diminished by it. 

 Another glandered horse took sublimate for a month, without 

 receiving any benefit from it. M. Ilouba, a French veterinarian, 

 gave an ounce of sublimate in a mucilaginous decoction, to a colt 

 of one year old affected with farcy. He increased the dose of 

 sublimate until it amounted to 2 ounces, 3 drachms, 21 grains, 

 or 64 grammes (a gramme is 18 grains). This immense dose, 

 lie says, after some days, made the ulcers look red, the discharge 

 lost its offensive smell, and became whiter and thicker, and some 

 of the ulcers cicatrised ; the colt also fed Avell and appeared 

 cheerful, but after a short time he began to discharge at the 

 nostrils, and had a swelling under the jaws ; in short he became 

 so badly glandered that it was thought necessary to destroy 

 him. (See Dupuy, De V Affection Tuherculeuse, vulgairement ap- 

 pelee Morve, p. 188.) 



Sublimate is often used externally, either in powder or solu- 

 tion. It is a useful caustic and external stimulant, and is 

 sometimes an ingredient in blisters ; but its employment in this 

 form is not to be recommended. 



In virulent cases of chronic grease I have seen a solution of 

 sublimate effect a cure in a very short time. 



In obotinate cases of mange a solution of sublimate is some- 

 times employed ; but in three instances I have known inflamma- 

 tion of the bowels take place very soon after. 



Sublimate is difficult of solution in water only ; it is usual, 

 therefore, to rub it first in a mortar with a little proof spirit, or 

 with a little muriate of ammonia ; but the most ready method of 

 dissolvino- it is to rub it with an equal vrcight of muriatic acid. 



