50 VETERINARY MATERIA MEDICA. 



Tinctura CinchoncE Comjjosita, compound tinc- 

 ture of cinchona bark, U. S. P. (Red bark 10, ser- 

 pentaria 2, orange peel 8, glycerin 10, alcohol and 

 water, of each a suflScient quantity to make 100 

 parts.) Dose: H., fl. $i.-iij.; D., fl. 3 ss.-iv. 



Infusum Cinchonce, infusion of cinchona. (Cin- 

 chona 6, aromatic sulphuric acid 1, water 93.) Dose: 

 H., Oss.-i. ; D., fl. 3 i.-iv. 



Quinince Siiljjhas, sulphate of quinine. Dose: 

 H., gr. XV.- 3 i.; D., gr. i.-v. 



Cinchonidince Sulphas^ sulphate of cinchonidine. 

 Dose: H., 3ss.-ij.; D., gr. ij.-x. 



Quinince Bimuriatis Carbamas, the double hy- 

 drochlorate of quinine and urea, a very soluble salt, 

 is especially adapted for hypodermic medication. 

 Dose for dog, inject grs. 1-^ to 8 dissolved in tt[ 10 to 

 20 of distilled water; dose for horse, inject grs. 15 to 

 30 dissolved in fi. 3 ss. to ij. of distilled water. 



Other quinine salts, as the muriate and bisulpliate^ 

 are given in the same doses as the sulphate. 



Incompatibles are free tannic acid, iodine, alkalies, 

 and alkaline carbonates. 



Physiological Action. — Cinchona bark is an 

 astringent bitter tonic, antiseptic, antiperiodic, anti- 

 phlogistic, antipyretic, and emmenagogue. It di- 

 minishes reflex action, acts as a protoplasmic poison, 

 and its alkaloids, while rapidly diffused, are but 

 slowly eliminated, being found in the urine in fifteen 

 minutes after taking, and as late as three days after; 

 the maximum point of action being reached in about 

 four to five hours after its first administration. Qui- 



