138 VETEKIXARY MATERIA 3IEDICA. 



excited, and delirious than relapsing into a sleep or 

 coma ; the same is true of the bovine species. Again, 

 in both of these animals the pupil does not always 

 respond to the action of the drug, neither is diapho- 

 resis so readily induced by it as in man. The dog, 

 however, is more susceptible to this drug than the 

 equine or bovine, and although after a brief period 

 of excitement these animals are overcome by its ac- 

 tion, they are quite readily awakened. Particular 

 individuals of all these species, however, will be 

 found quite susceptible to the action of opium and its 

 preparations. The writer injected subcutaneously 

 morphine sulphate 3 i. in a mare of one thousand 

 pounds at 9 P.M. In fifteen minutes the animal ap- 

 peared slightly drowsy, but rapidly became nervous 

 and excited ; by 9 :30 P.M. the pulse was increased both 

 in force and volume, respirations slightly stertorous. 

 10 p. M: Forty-five grains more ^vere injected; pulse 

 continued, strong and bounding, increased nervous 

 excitement, pupils somewhat dilated. 12 P.M.: The 

 animal appeared still in about the same condition, and 

 at 3 A.M. gr. Ix. more were injected; the pulse was 

 now somewhat weaker than before and respirations 

 irregular and laborious. G a.m. : The last symptoms 

 aggravated, pulse very weak and irregular, nervous 

 excitement much abated, insensibility to pain. 8.30 

 a.m. : Great dulness, cold sweat, pulse very small and 

 weak, respiration jerky and irregular, pupils con- 

 tracted. Death took place at 9 a.m. Post-mortem 

 examination showed a wet brain, congested lungs, 

 blood fluid and dark-colored, engorgement of the 



