MORBID ANATOMY 99 



The duration of the disease is short. Often the animals 

 are found dead. 



The prognosis is unfavorable. The mortality is placed at 

 from 80 to go per cent of the animals affected. 



§ 82. Morbid anatomy. The characteristic lesions of 

 the disease are widely distributed areas of hemorrhage, vary- 

 ing in size from a pin point to several centimeters in diameter. 

 They vary in color from light red to almost black. They are 

 frequently accompanied with a sero-fibrinous exudate, usually 

 yellov^, but occasionally dark red in color. The hemorrhagic 

 areas in the animals just dead are not so dark as those in 

 animals that have been dead for some hours. The large areas, 

 some centimeters in diameter, are apparently due, in some 

 instances at least, to single hemorrhages, infiltrating an exten- 

 sive mass of tissue, and in others to a number of minute hem- 

 orrhages closely placed and partially coalescing. Gas is not 

 present in the subcutaneous connective tissue except in cases 

 where extensive post-mortem changes have occurred. 



There is extensive fullness of the vessels of the subcu- 

 taneous connective tissue in the acute cases, especially in 

 those animals which are not killed by bleeding. In animals 

 which live until emaciation is marked, there is no engorgement 

 of the vessels. 



Reynolds reports one outbreak in which meningitis 

 involving the spinal cord, brain or both of these organs were 

 invariably present. 



All cases show some hemorrhagic areas in the subcutane- 

 ous tissue, though the number and size of these vary greatly 

 in the different cases. Some animals show not over a dozen 

 areas between two and three centimeters in diameter, though 

 many minute cues are present. In other animals, on remov- 

 ing the skin, hemorrhagic areas are found in great numbers 

 and so extensive that a large fraction, possibly one-eighth, 

 of the body surface appears to be involved. The large hemor- 

 rhages in the subcutaneous connective tissue appear to be of 

 the composite type noted above. 



