MORBID ANATOMY 



i6i 



gangrenous. In nodular and in infiltrated glanders of the 

 lungs, the bronchial glands and frequently the mediastinal 

 glands become enlarged, indurated and studded with small 

 foci of cell infiltration. 



In glanders of the skin (farcy) the nodules are found in 

 the papillary layer, in the cutis and in the subcutaneous and 

 superficial intermuscular 

 tissue. The cutaneous 

 nodules vary in size 

 from a hemp seed up to 

 a pea. They suppurate 

 rapidly and form small 

 ulcers. The nodules in 

 the subcutis are inflam- 

 matory (metastatic) tu- 

 mors from the size of a 

 pea to that of a hen's 

 egg. They change into 

 lar^e abscesses and dis- 

 charge externally. In 

 the region of the nodules 

 the lymphatic ve.ssels 

 are inflamed, swollen, 

 and frequently resemble 

 a rosary or knotted cord. 

 Ulcers often develop 

 from these secondary 

 nodes. The neighbor- 

 ing lymph glands are at 



' A«^*^ .^ 





Fig. 28. Section of a glanders nodule 

 in the lung of a horse: (a) necrotic center, 

 {c) zone of giant cells, {b) capsule sur- 

 rounding the nodule [Schiitz). 

 first swollen and soft, 



but later they become indurated by the growth of connective 

 tissue and studded with dirty white nodules about as large as 

 a pin head, or with yellow foci of caseation. The capsule 

 around the lymph glands becomes infiltrated with small cells 

 and subsequently thickened. In rare cases secondary chronic 

 farcy occurs. It is marked by a large, diff"use new growth of 

 connective tis.sue with nodular thickening of the skin. This 



