MORBID ANATOMY 327 



points where this infiltration occurs quite extensively. In 

 some of the preparations the wandering cells have been traced 

 as far as the surface of the epidermis. 



Occasionally there may be found a narrow area at the 

 periphery of the nodule, as seen 

 in cross section, which is lighter 

 in color and less dense in text- 

 ure than the central mass, evi- 

 dently an extension of the 

 growth. 



In the specimens examined 

 the parts where the lesions 

 abounded were not character- 

 ized b}' a rich vascular supply. Fig 82. From the same Up, but 

 The few vessels that were en- shoiving a larger infected area 

 countered were not of a normal i^^^'^)- 



character ; their walls were thickened, and the endothelium, 

 instead of presenting the usual flattened appearance, was 

 irregularly cylindrical. Although the condition was not ob- 

 served, it is not impossible that the hyphae of the fungus may 

 develop to such an extent as to compass or actually penetrate 

 the walls of the vessels, causing inflammatory changes suffici- 

 ent to permit, in the course of time, a disorganization or ab- 

 sorption of a portion of the vessel itself, and that ultimately it 

 may become incorporated in the nodule. 



DESCRIPTION OF FIG. 81. 



1. Showing a yoiDig Jiiugus embedded in the tissues [lif>). 



2. Showing scale-like bodies embracing the filaments. 



3. Showing young branches of the fungus, and in one place the 

 transparent sheath. Hematoxylin preparation. 



4. Mycelium with scale-like bodies lying among the filaments. 

 Hemato.xyli?i. 



5. Vacuolated filaments. Honato.rylifi. 



6. Branches showing a 7cell developed, transparent sheath. In 

 places the axis of the branch is disconnected and occasionally there is 

 a faint sign of a septum. Hematoxylin. 



No. 4 ocular, 2 mm. objective. Camera lucida {After Fish). 



