412 



DOURINE 



Rouget in 1896, described a trypanosoma found in the 

 blood of a horse suffering from dourine, and for over two years 

 continued the study of this organism in susceptible animals. 

 Wasilewsky and Senn confirmed Rouget's work, and deter- 

 mined the pathogenic action of this trypanosoma for the horse, 

 passing it through other animals and back to the horse, repro- 

 ducing the disease. Laveran and Mesnil (igoi) proposed the 



Fig. 108. Tr. eijuiperduiii. i , in the blood of a mouse Jour days after 

 inoculation, 2, same blood eight days after inoculation {after Rouget). 



name Tr. rojigetii for the parasite of dourine. Doflein named 

 it Tr. eqziiperdiim , which is the name used by Salmon and 

 Stiles. 



In its morphology and evolutionary forms, the trypano- 

 soma of dourine has not been shown to differ from that of 

 surra. The granule form, the spherical, the club shaped or 

 pyriform bodies, the fusiform with more or less stellate group- 

 ings seem to be generic characteristics. Baldrey states that it 

 is smaller than the Trypanosoma of Surra. The specific dis- 

 tinction is found in the pathogenesis as shown by the two 

 diseases (surra and dourine). 



In the active stages, the parasite is usually found abund- 

 antly in edematous fluid, the blood, semen, milk, vaginal 

 secretions and the erosions of the vaginal mucosa and penis. 

 During intermissions, however, and in the absence of local 

 lesions, the parasites are not found in the blood on micro- 

 scopic examination, yet the inoculation of the blood into 



