41 6 , DOURINE 



enlarged, protruding, unnaturally dry clitoris, especially in 

 young and otherwise healthy mares is quite pathognomonic." 



Instead of urine small quantities of sticky, discolored 

 mucus are discharged. The animals incessantly shake their 

 tails and open and close the vagina in rapid succession, show- 

 ing the clitoris as mares do in season. The discharge often 

 exerts a corrosive action on the tail and legs. In severe cases 

 the neighboring lymph glands become inflamed and swollen as 

 well as the udder, on which abscesses may appear. The 

 swelling may even extend to the hypogastrium. 



The general symptoms develop only after weeks or even 

 months; their appearance is often delayed until the local 

 symptoms have disappeared. At first the animals are de- 

 pressed and weak, they frequently continue to lift up their 

 hind feet, alternately, so as to try to avoid putting weight 

 upon them, knuckle on their fetlock joints and lose control 

 over the movements of their hind legs while walking. The 

 temperature is not so high as in other forms of Trypanosma 

 infection. 



It is reported that stallions especially suffer from an 

 urticaria in the form of sharply defined, round, flat eminences 

 which may be raised the breadth of a finger above the surface 

 and which may vary in size from two to four centimeters or 

 more in diameter. These eminences are caused by a serous 

 infiltration of the papillary layer of the skin in the neighbor- 

 hood of a small artery and are evidently of a vaso-neurotic 

 character. They often appear and disappear very rapidly and 

 may shift their position. Usually they persist for several 

 weeks during which time they become moderately hard and 

 then slowly disappear. Their favorite sites are the croup, 

 neck, shoulders, chest and abdomen. 



Later in the course of the disease, a progressive paralysis 

 of the hind quarters combines with excessive emaciation. The 

 animal has a staggering gait and often gives way on the pas- 

 terns and at the knees, can raise itself from the ground only 

 with difficulty, and sometimes falls down unexpectedly. The 

 affected stallion is unable to cover, as he can neither mount a 



