PREVENTION 453 



mention Haubner, Bouley. Schiitz and others, start from the 

 well known fact that one attack of pleuro-pneumonia success- 

 fully passed through confers immunity for the remainder of 

 the'animal's life. By inoculation, a local, specific, inllamma- _ 

 tory process which is analogous to that in the lungs, is pro- 

 duced and is followed by subsequent immunity of the whole 

 body. Haubner calculates that the mortality from the inocu- 

 lation is from i to 2 per cent and that the tips of the tails are 

 lost in from 5 to 10 per cent of the cases. In Holland, among 

 59,180 cattle inoculated in 1878 and 1879, the mortality 

 amounted to only 0.66 per cent. 



The opponents of inoculation, among whom we may men- 

 tion Rolof, Ziindel. Kitt, M'Fadyean and others, assert that 

 up to the present no positive case of immunity has been proved 

 to have been obtained from inoculation. They also point to 

 the fact that even the advocates for inoculation are unable to 

 give the exact duration of the immunity and consequently 

 make several inoculations. Dujardin-Beaumetz finds that the 

 inoculation in the tail with a bouillon culture of the organism 

 gives a local swelling. It confers immunity quite as well as 

 the injection of the serous fluid. Already he reports its use 

 in 675 cattle, of which 14 died as a result of the inoculation. 

 The best procedure seems to be the stamping out of the dis- 

 ease by means of thorough disinfection or destruction by fire 

 of all infected sheds and barns. The success of this method 

 is illustrated by the eradication of the disease from the United 

 States. 



REFERENCES 



I. DUJARDIN-BEAUMETZ. Le microbe de la peripneumonie et la 

 culture. Thi'sis. Paris, 1900. 



2 Noc^RD EX Roux. Le microbe de la peripneumouie. Recueil 

 de MM VHerinaire, March 24, 189S, p. 212. ( Trans, in the Veterinary 

 Journal, London, Vol. XLVII (1898), p. 147- Ann. dc Vlmt. Pasteur, 

 Vol. XII (1898), p. 240.) 



3. Salmon. Annual Reports of tlw Bureau of Animal Industry, 



I 884-1892. 



4. SMITH. Annual Report of the Bureau of Animal Industry, 



1895-6, p. 143- 



