544 FOWL PEST 



present in the proportion of i to 125,000,000 destroyed a 

 5'oung hen. 



The virus retained its virulence in blood for 15 davs. It 

 was destroyed in thirty minutes at a temperature of 60° C. 



S 437- Symptoms. According to Centanni the chicken 

 acts dumpish the first day and refuses food on the second. 

 The feathers are ruffled, the comb discolored and on the third 

 day it dies. More rapidly fatal cases are mentioned by Lode 

 and Gruber. The temperature is at first high but it falls to 

 subnormal before death. 



§ 438. Morbid anatomy. The lesions vary. In some 

 cases death follows so rapidly that autopsies reveal no change. 

 Usually there is a slight pericarditis and ecchymoses in the 

 heart muscle. There is pleurisy in some cases. The lungs 

 are congested and occasionally there are pneumonic centers. 

 The liver, spleen and kidneys are more or less congested. 

 Microscopic changes are not described. 



§ 439. Differential diagnosis. This is to be differen- 

 tiated from fowl cholera and typhoid. The diagnosis is made 

 from the bacteriological examinations. The rapid cour.se of 

 the disease cannot be relied upon as a differential character, 

 for both fowl cholera and fowl typhoid often run very 

 rapid courses and likewise have a high mortality. 



REFERKNCES. 



1. Centanni. Die Vogelpest ; Beitrag zu dem durch kerzen 

 filtrirbaren Virus. Cent. f. Bakt. Bd. XXXI (1902), vS. 145. u. 182. 



2. Dubois. Une maladie infectieuse des poules a microbes invisi- 

 bles. Conip. Rend. Sac. de biol. \o\. LIV (1902), p. 1162. 



3. Leclainche. Revue Generate de Med. Veterinaire. 1904, p. 

 49. Abstract of article in Jota-. Comp. Patti. and Thera. Vol. XVII 

 (1904), p. 83. 



4. Lode und Gruber. Bakteriologische vStudien iiber die Aeti- 

 ologie einer epidemischen Erkrankung der Hiihner in Tirol (1901). 

 Central-blati fin- Bafct. Bd. XXX (1901), S. 593. 



5. Maggiora und Vai^enTI. Ueber eine Seuche von exuda- 

 tivem Typhus bei Hiihnern. Zeit fur. Hvgiene, Bd. XLII (1903), S. 

 185. 



