142 Diseases of the Getiital Organs 



the drug. Autopsy showed enlarged, congested genital 

 canal, prominent ripe ova, etc. 



In experiments on young bitches less than nine months 

 old, the drug, in fatal toxic doses, failed to cause reaction in 

 the genital organs. 



I used the drug experimentally upon several cows in 

 which I had otherwise failed to induce estrum, but, like 

 other efforts, it was without avail. In one cow there were 

 ovarian adhesions; in another, cystic degeneration of the 

 ovaries, etc. The drug has dropped out of notice except for 

 an occasional medicine vendor who adheres to "patent medi- 

 cine" ideals. The failure of an adult, non-pregnant female 

 to come in estrum at the proper time is due to some patho- 

 logic condition, the removal of which is followed by estrum. 

 But the removal of the cause of non-estrum must be the 

 basis for action in each case. These pathologic conditions 

 will be discussed in their proper places. In some cows es- 

 trum is not very evident, or the keeper fails to recognize it. 

 The animal may be healthy or unhealthy. It is important 

 in some healthy cows to get definite track of the estrum. If, 

 upon the examination of an animal in which estrum is not 

 observed, the general health is good, the genital organs nor- 

 mal, and a corpus luteum present, it is sufficiently clear that 

 at some former date the animal had been in estrum and had 

 ovulated. If the corpus luteum is dislodged by compressing 

 it per rectum, the animal will quite certainly be in estrum 

 in three or four days. 



In some cases it is desirable to interrupt the estrual cycle 

 because several females are in estrum simultaneously and 

 the service of all would overwork the herd bull. The vet- 

 erinarian can, by dislodging the corpus luteum, adjust the 

 estrual cycle at will. 



Healthy cows sometimes fail to ovulate promptly after 

 parturition, thereby causing a delay in re-breeding. When 

 a cow does not show estrum within sixty days after par- 

 turition, if she is healthy, the corpus luteum of pregnancy 

 is probably tardy in disappearing. It then becomes of im- 

 portance to the dairyman that the yellow body shall be dis- 

 lodged and the cow caused to come in estrum. 



