PHYSIOLOGY 



by injecting a very minute quantity of it into the 

 circulation of an animal. Whether histamine is 

 really the only poison that acts in these cases of 

 crushed tissue and secondary shock is one of the 

 questions for the future, but, at any rate, if there 

 is any other it must be a poison that acts in a similar 

 way and probably has a similar origin. 



I have taken the above as another example of 

 the importance of attention to minute details, and 

 again it illustrates what is so frequently, indeed 

 almost universally, illustrated throughout recent, 

 and I expect will be illustrated in future, physio- 

 logical work namely, that the ' next-to-nothings ' 

 often prove to be of supreme importance in solving 

 the puzzles that perplex investigators. 



W. D. HALLIBURTON 



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