MALIGNANCY 59 



ship between epithelium and connective tissue, and suggest 

 that a morbid condition of the pituitary may be a funda- 

 mental cause of the disease. 



7. Malignancy is thus brought into relation with the 

 phenomena of growth, and can be classed with develop- 

 mental diseases, such as those due to endocrine atrophy 

 or hypertrophy. 



8. Research should be directed to the discovery of the 

 tissue products or secretions by which epithelium and 

 connective tissue preserve their individuality and prevent 

 reversion in each other. 



REFERENCES. 



Adami, J. G. — " Medical Sidelights on Evolution," 1919. 

 Bainbridge, W. S. — " Cancer Problem," New York, 1914. 

 Bayliss, W. M. — " Principles of General Physiology," 1915. 

 Bland-Sutton, Sir John. — " Tumours," 1918, Lecture III., 



Chem. Journ., vol. xxx. pp. 186-208. 

 Butlin, Sir H. — " Unicellula Cancri," 1912. 

 Darier and Wolbarth. — Quoted by Hartzell, M. B., " Diseases 



of the Skin," 1917. 

 Erlich, P., and Apolant, H. — " Mouse-Tumours," Berlin Klin. 



Woche, July 1905. 

 Green, C. E. — " Cancer Problem," 1919. 

 Handley, Sampson. — "Melanotic Sarcoma," Hunterian Lecture, 



1907, Lancet, London, 1905, vol. i. p. 909 ; ibid., 1907, 



vol. i. p. 930; "Paget's Disease," Brit. Journ. of Surgery, 



vol. vii. No. 26, 1919. 

 Hernaman-Johnson, F. — " Comparative Value of X-rays and 



Radium in Malignant Disease," Aberdeen, B.M.A. 

 Kettle, E. H.— "Pathology of Tumours," 1916; Path. Sect., 



R.S.M., April 15, 1919. 

 Knox, Robert. — " Radiology," 1918. 

 Murphy, J. B., and Sturm, E— Journ. Exper. Med., Jan. 



1919, iii. 

 Paget, Sir James.—" Lectures on Surgical Pathology," 1N53. 



