ON SPECIFIC THERAPEUTICS. 35 



In the cases of liver affections, on the other 

 hand, the following results were obtained : 



(1) Carcinoma of the bile ducts with complete 

 bile stasis: 0*5 ro c.c. serum, death on the 

 fifth day ; 2*0 c.c. serum, death on the eleventh 

 day. 



(2) Carcinoma of the stomach, with jaun- 

 dice, 0*1 0*25 c.c. serum, death on the fifth 

 day. 



(3) Alcoholic cirrhosis of the liver, 0*125 c.c. 

 serum, death on the sixth day. 



(4) Biliary cirrhosis with jaundice, 0*125 c.c. 

 serum, death on the seventh day. 



(5) Alcoholic cirrhosis of the liver, 0*125 c.c. 

 serum, death on the eighth day. 



(6) Biliary cirrhosis with jaundice, 0*125 c.c. 

 serum, death on the thirteenth day. 



Thus there was observed in every instance, 

 with the exception of case 6, a distinct, though 

 varying, deficiency in the trypanosomicidal pro- 

 perties of the serum, and that this deficiency 

 was not merely an apparent one, produced by 

 the presence of inhibiting substances, e.g., the 

 products of bile stasis, was shown by experi- 

 ments in which a mixture of equal parts of the 

 serum from case i and from the acromegaly 

 case were injected : 0*5 c.c. of the mixture, 



D2 



