HIGHER FISSION-FUNGI. 457 



necrophorus Flugge, Necrosis bacillus Bang (C. B. xm, 

 201). Streptothrix cuniculi Schmorl. Actinomyces cuni- 

 culi Gasp. (Deut. Zeitschr. f. Tiermed., xvn). The or- 

 ganism lies in the necrotic tissue (diphtheritic membrane, 

 etc. ) on the side turned away from the surface as long, 

 often radially arranged meshes or bundles, separated from 

 healthy tissue by a narrow, necrotic zone. It is an obli- 

 gate anaerobe, growing best on blood-serum or blood-serum 

 agar at incubator temperature, and has been incompletely 

 described as to its morphology (branching!). It is of great 

 practical interest as the cause of numerous diseases in ani- 

 mals. It was cultivated by Schmorl from a destructive 

 epidemic in rabbits, and first described .by Loifler as the 

 cause of calf diphtheria (mouth, larynx, nose). Accord- 

 ing to Bang, it also causes in young and old cattle, horses, 

 and swine the most various necrotic affections (panar- 

 itium, gangrenous pock, intestinal diphtheria, liver ab- 

 scess, vaginal and uterine diphtheria, etc.). We were un- 

 able to study this evidently important organism. 



Regarding thermophilic varieties of actinomyces, see Kedzior 

 (C. B. L. in, 154) and Tsiklinsky (C. B. xxv, 385). 



After subcutaneous inoculation of mice, Loffler obtained the picture 

 of progressive connective-tissue necrosis. A layer of lardaceous infil- 

 tration extends subcutaneously from the point of infection and envel- 

 ops the kidneys, liver, and intestine with yellowish masses of exu- 

 date. According to Loffler, rabbits are not affected characteristically; 

 but according to Schmorl and Bang, they are. All investigators found 

 other experimental animals to be immune. 



APPENDIX II. 



Higher Fission-fungi. (Higher Fission- 

 algae.) 1 



The close relationship with the chlorophyllaceous algae 

 is still more evident in the varieties of this section than in 



1 We have had little personal experience with this group, and 

 limit ourselves partially to a critical review of the literature. 



