

BACILLUS OZMN& 365 



Type I. All carbohydrates and starch fermented with the produc- 

 tion of gas (H:CO 2 =f) and acid; Bacillus lactis aerogenes. 



Type II. All carbohydrates except saccharose fermented; starch 

 fermented Bacillus mucosus capsulatus, Bacillus rhinoscleromatis, 

 Bacillus ozsense. 



Type HI. All carbohydrates except saccharose and starch fer- 

 mented; Bacillus acidi lactici. 



Enzymes and toxins have not been demonstrated in cultures of any 

 members of the group. 



Pathogenicity. Human. Bacillus mucosus capsulatus has been 

 isolated in a considerable proportion of cases of lobular pneumonia, 

 but it practically never is the sole incitant of lobar pneumonia. It 

 is occasionally detected in purulent inflammations of the respiratory 

 tract not pneumonic in character, in the purulent secretions of the 

 nasal and frontal sinuses, in occasional cases of pericarditis and 

 pleurisy, stomatitis and otitis media. The normal sputum occasionally 

 contains the organism. 



Animal. Subcutaneous inoculations into mice, rabbits or guinea- 

 pigs frequently lead to abscess formation characterized by thick, 

 viscid pus. Occasionally a generalized infection which results fatally 

 takes place. 



Bacillus Rhinoscleromatis. Rhinoscleroma, characterized by 

 indurated granulomatous nodules of the mucous membrane of the 

 nose, is ascribed to Bacillus rhinoscleromatis by v. Frisch, 1 Paltauf 

 and v. Eiselsberg, 2 and others. A satisfactory demonstration of the 

 etiology of this infection is wanting, but organisms culturally like 

 Bacillus rhinoscleromatis have been isolated from the cells of Miculicz, 

 large, swollen cells with crescentric nuclei characteristically present in 

 rhinoscleroma and demonstrated within them on section. 



Bacillus Ozsense. Ozena, a disease of the nose characterized by a 

 fetid catarrhal inflammation, is very frequently associated with the 

 presence of large numbers of a member of the Mucosus Capsulatus 

 Group to which Abel 3 gave the name Bacillus ozsense. The organism 

 has not been sharply separated from Bacillus rhinoscleromatis and 

 Bacillus mucosus capsulatus, and its etiological relationship to ozena 

 is still sub judice. Autogenous vaccines of the organism have been 

 used with varying success in the treatment of the disease. 



1 Loc. cit. 



2 Fort. d. Med., 1886, Nos. 19 and 20. 



3 Loc. cit. 



