554 TRICHOMYCETES, ACTINOMYCETES, HYPHOMYCETES 



Blastomycetes Group from a cutaneous infection of horses, and San- 

 felice 1 recovered a similar organism from a lymph gland of an ox which 

 had a generalized carcinoma. This organism was pathogenic for 

 white rats, rabbits, guinea-pigs, sheep and cattle. 



The defensive mechanism which tends to limit the spread of the 

 organism in the body is largely phagocytic, together with a prolifera- 

 tion of regional connective tissue which tends to encapsulate and then 

 restrict the progress of the lesion. 2 



The diagnosis of blastomycetic infections is best made by a micro- 

 scopical examination of the contents of a papule or pustule teased 

 out in diluted NaOH, and unstained. 



1 Centralbl. f. Bakt., 1895, xviii, 521. 



2 Christensen and Hektoen, Jour. Am. Med. Assn., 1906, xlvii, 247. Davis, Jour. Inf. 

 Dis., 1911,viii, 190. 



