SPIRILLUM DEN EKE. 263 



very slight. No growth occurs in either tap-water or steril- 

 ized water. There is no cholera-red reaction. When grown 

 in a medium containing glucose, acid is produced. The 

 organism resists desiccation much better than the cholera 

 spirillum. 



Pathogenesis : Although the organism is pathogenic for some 

 animals, it does not appear to be the cause of disease in man. 

 It is most frequently found in the intestinal discharges of per- 

 sons suffering from diarrhoea or cholera nostras. It may occa- 

 sionally appear in the feces of healthy patients. 



Spirillum Deneke (Vibrio Tyrogenum). 



Deneke obtained this organism from old cheese. 



Biology and morphology: The Spirillum Deneke resembles 

 the cholera spirillum even more than does the Finkler-Prior 

 spirillum. It is a very short curved rod, a number of which 

 may form tightly coiled chains and spirals (Fig. 116). It is 



FIG. 116. 



Spirillum tyrogenum. X 700. (Fluegge.) 



flagellated and actively motile; stains like the cholera bacillus; 

 grows equally well at the room and body temperature ; and 

 does not form spores. It is a facultative anaerobe. 



The colonies on the gelatin plate differ from those of 

 cholera in that they develop more rapidly, are of a yellowish- 

 green color, and are irregular in contour, with sharply defined 

 borders (Fig. 117). The medium is also liquefied more 

 rapidly. 



In the gelatin stab the stocking-shaped liquefaction is 

 formed, which is filled with the cloudy liquid, the culture col- 



