History of Aiiiuial Plagues. 337 



fluids, the cud forming a dry concreted mass. At the same time, 

 nevertheless, the ghuids of the nose and eyes are rendered more irrit- 

 able, and the humours are secreted in them much more copiously than 

 the natural degree. The paralytic disorder of the saliva! glands, and 

 the glands of the stomachs, extends itself frequently in the tirst stage to 

 those of the small guts, as may be inferred from the cos tiven ess observed 

 at that time. But this often changes afterwards into a great irritability 

 in the second stage, as is evinced by the profuse diarrhoea attending. 

 On the other hand, the irritability of the glands of the nose and eyes 

 seems to be continued to the membranes of the lungs by the cough, 

 which is almost a constant symptom. The stomachs seem also to par- 

 take of the paralysis of the upper parts, and this appears to be in pro- 

 portion to their nearer situation to those parts, as may be inferred from 

 the retention of the cud in the cud-bag and honey-comb, and the 

 emptiness of the cud-bag. There is an early etfort of nature to make 

 an expulsion of the morbid matter by the external parts of the head, as 

 may be collected from the signs of topical inflammation which show 

 themselves, and particularly about the horns, \\'here abscesses are after- 

 wards frequently formed. But this alone rarely proves a critical dis- 

 charge. 



* After the first four days the contagion diffuses its eff'ects much 

 more generally, and frecjuently attacks the liver and the lower intestines, 

 which then become very irritable ; a great discharge of bile, and tlie 

 other humours secreted in them, ensuing. But the inactive or paralytic 

 state of the salival glands and those of the stomach yet goes on increas- 

 ing, till all secretion by them ceases. Hence the appetite and digestion 

 are entirely lost ; and the inanition, caused by the want of a due supply 

 of chyle to the blood, conspires greatly, with the nervous debility above 

 speciried, to bring on a great languor of the circulation and other vital 

 action. This necessarily induces a putrescence of the juices; whence 

 new sensible effects are produced, which may be deemed secondary 

 symptoms; being not the immediate consequences of the action of the 

 contagion, but the effects of the putrid ferment sutfered to prevail by 

 the suppression of the animal ferments, wdiich counteracted it while 

 they subsisted in the due degree. In this difference of the cause of the 

 symptoms, principally consists the difference of the first and second 

 stages of the disease ; the first exhibiting those alone which result from 

 the action of the contagion on particular parts, and may, therefore, be 

 called primary ; the second displaying not only a further extension of 

 such symptoms, but those others also that are caused by the general 

 depravity of the fluids, and the consequential disorder of the vital 

 economy, which arise frcjm the putrescence that prevails from the weak 



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