Atrophy of Bone. 205 



The metatarsals are extremely thin, and are ossified 



together at their bases. The three cuneiforms and the scaphoid 



are also ossified together. The os calcis and the cuboid are 



widely separated. The cancellated tissue is very light, and in 



many places has disappeared. The bones were fairly easily 



cleared of fat. G. C. 2820. 



Presented by P. H. Maclaren, F.R.C.S.E. 



For other examples of atrophy from disuse, see "Stumps," series 11. 

 For atrophy from continuous pressure, see series of General Pathology. 



6. 16. Changes in Bone from Peripheral Nerve Lesion.— 



Specimen wanted. 



C. Changes from affections of the central nervous system. 

 6. 1 7. Alterations in Skeleton in a Case of Paralysis and 



Idiocy. — Skeleton of a woman, showing the above. The 

 following description has been kindly furnished by the donor. 



" This specimen was obtained from the body of a woman aged 30, 

 who died in the Norfolk County Asylum in 1891. Of a neurotic family, 

 she was apparently healthy and well-formed at birth. When she was a 

 year old, on attempting to stand, the weakness of the right arm and leg 

 were noticed. The weakness increased, and the affected members became 

 drawn up. She never walked. The recumbent position was adopted, and 

 maintained from infancy till her death. She never moved the right arm 

 or leg. She could move the head and grasp objects with the left hand. 

 She suffered from convulsive fits from the age of 3 till the age of 26. 

 She was a complete idiot." 



"The skull is typically micro-cephalic; it is also asymme- 

 trical, the right half of the cranial box being greater in its 

 dimensions and more convexly arched than the left. This 

 assymmetry is the result of a lesion in early life of the left 

 cerebral hemisphere of the brain, whereby the growth of the 

 latter was interfered with." 



The bones of the trunk and extremities present features 

 which are to be etiologically associated with a right-sided 



