2 24 : Discas es of Bon c. 



and from which the osseous covering had been removed witliout the least 

 hsemorrhage ; in short, it ap[ieared to me an unorganised mass, similar to 

 tlie flesh-like substance or coagulum which may be formed upon a stick or 

 feather by stirring fresh blood in a basin." 



The pains continued, and the right thigh and leg became more and 

 more distorted, followed by a similar change in the left thigh and leg. 

 His appetite remained good. His urine, for about two years, "deposited 

 a whitish sediment, which, upon evaporation, became like mortar." 



He became gradually weaker, and died on 18th February 1775. 



At the post-mortem examination all the bones of the body 'were 

 quite soft, and easily cut with a knife. " All these originally bony parts 

 consisted of a mere cortical or outside osseous covering of the thickness of 

 rind of cheese, and of an inside flesh-coloured mass." (See " Medical 

 Observations and Enquiries by a Society of Physicians in London : Paper 

 by Mr Henry Thomson ; vol. v, p. 259. ) 



The greater part of the cancellous tissue is absorbed, and 

 the outer shell is extremely thin and soft, and composed appar- 

 ently, for the most part, of fibrous tissue. W. C. G. 36. 



6.55. Osteo-malacia of the Lower Limbs— Eight lower 



limb — dried and in spirit, showing the above. 



" From a young dwarf, affected with the mollities ossium." 

 The bones were quite soft, and the limb is bent so that the 

 bones of thi^h and leg form alternating curves. W. C. G. 35. 



(c.) Ostitis Deformans. 



6. 56. Ostitis Deformans of the Skeleton.— Photograph of 



the front view of a skeleton in the Museum of the Eoyal 

 College of Surgeons, where the patient had been affected by 

 this disease in most of the long bones and in the skull. (From 

 the "Illustrated Medical ^^ews," February 23rd, 1889.) 



G. C. 3583. 



6. 57. Ostitis Deformans of the Skeleton.— Photograph of 



a patient affected with ostitis deformans. (From the " Illus- 

 trated Medical News," February 23rd, 1889.) G. C. 3584. 



