Syphilitic and Septic Disease. 331 



7. Inflammation of Bone due to Syphilis, complicated hy Sepsis. 

 6. 338. Syphilitic (?) Disease of the Tibia and Invasion by 



an Ulcer. — Portion of a right tibia — macerated, illustrating 

 the above. 



Nearly all round the bone there is a thickening, which, 

 to judge from the rarefaction on its inner surface, has 

 probably formed the base of an ulcer. B. C. i. 5. M. 6. 



6. 339. Syphilitic (?) Disease of the Tibia and Invasion by 



an Ulcer. — Lower end of the right tibia of a young man- 

 macerated. The epiphysis has not yet united. 



There is an enlargement on the inner aspect near the 

 lower end, and the surface there is rarefied and depressed, as 

 if it had formed the base of a deepening ulcer of the soft 

 parts. 



This specimen has been considered syphilitic from the 

 node-like character of the swelling, the comparative youth of 

 the patient, and the absence of such surrounding periosteal new 

 formation as is commonly associated with ordinary ulcera- 

 tion. B. C. I. 5. M. 65. 



6. 340. Syphilitic Disease of the Tibia, with Invasion by 



an Ulcer. — Portion of a left tibia — macerated, illustrating 

 the above. 



On the shin surface there is a node, which is excavated 

 and rarefied as if it had formed the floor of an extending ulcer 

 of the soft parts. Some new periosteal bone has been formed 

 up and down the shaft near the ulcer. G. C. 1007. 



6, 341. Syphilitic Disease of the Tibia, with Invasion by 



an Ulcer. — Eight tibia of a tall young man, with the epi- 

 physis not yet united — macerated, illustrating the above. 



