334 Diseases of Bone. 



A large mass of rough, and irregular bone near the middle 

 of the shin surface has apparently been a sequestrum in process 

 of separation, and has no doubt lain exposed on the floor of an 

 ulcer. Below this the bone is porous, as if it had formed the 

 base of an extending ulcer, and below this again there is a 

 raised mass of periosteal bone, which is penetrated here and 

 there by roughened apertures. The rest of the surface of the 

 tibia is rough from new periosteal bone formation. The section 

 of the bone shows a small central necrosis near the upper end. 

 Above this piece there is an excavation of the head of the 

 tibia, and below it the greater part of the medullary cavity is 

 occupied by cancellated tissue. G. C. 1179. a. 



Presented by Professor James Ritssell. 



8. Goiiibinecl Effects of St/philis and Rickets. 

 6. 346. Syphilis and Rickets of the Femur.— Left femur of 



an adult — macerated, illustrating the above. 



The specimen shows a rickety bend, with syphilitic nodes 

 on the surface. The bend is chiefly seen at the upper end, 

 and is an exaggeration of the normal curve, such as is usually 

 seen in rickets. The nodes occupy the front and outer part of 

 the shaft, and bear a close resemblance to the syphilitic nodes 

 seen in previous specimens. B. C. i. 5. M. 51. 



6. 347. Syphilis and Rickets of the Femur.— Right femur- 

 macerated, illustrating the above. 



The normal bend of the shaft is exaggerated above, and a 

 node has apparently been developed about the same place. 



This somewhat resembles the previous specimen, and may 

 be considered to have been a slight case of rickets to which 

 syphilis has been superadded. F. P. C. 603. 



Presented by Professor John Thomson. 



