Ostco-Sarcomata. 365 



was performed by Dr John Duncan, nearly a year after the symptoms 

 first began. The patient made an excellent recovery, and had returned to 

 business, when the disease appeared in the brain, and, after a few weeks' 

 illness, carried him off. 



The section shows the tumour to be growing round the 



outside of the bone, which is, however, also partly affected in 



the interior. The substance of the tumour is vascular, soft, 



and friable, with a few bony spicules. Under the microscope it 



is a large spindle-celled sarcoma. G. C. 3463. 



Presented hy Alexis Thomsox, F.E.C.S.E. 



6.410. Osteo - Sarcoma of the Lower End of Femur.— 



Anterior half of the lower end of a right femur — macerated, 

 illustrating the above. 



A somewhat lobulated tumour has grown from the inner 

 side at and above the knee-joint, and apparently contains bony 

 spicules. In the interior the tumour substance has invaded 

 the cancellous tissue. G. C. 2478. 



6. 411. Osteo-Sarcoma of Leg" and Foot.— Section of the lower 



part of a right leg and foot — in spirit, illustrating the above. 



"1828. — Mr B., aged 57, healthy and active, formerly of habits 

 unmarked by any peculiarity, about eight years ago, while travelling by 

 night on the outside of a stage-coach, had his legs and feet extremely 

 lienumbed with cold, and in a few days they were affected with severe pain. 

 The left leg soon grew permanently well ; the right leg never did. The pain 

 was seated in the shin-bone, varying according to the season and state of 

 the weather. About two years since, the anterior angle of the tibia had 

 become serrated {sic); in a few months afterwards a swelling of the perios- 

 teum appeared on the middle of the bone. This was reduced by a blister 

 and issue. In February 1827 the lower two-thirds of the bone were 

 become enlarged. Numerous processes from the anterior and posterior 

 angles distended the neighbouring muscles ; much thickening of the soft 

 parts round the lower end of the bone, and cedema of the foot. At the 

 end of three months, during which the treatment consisted of repeated 

 applications of leeches and blisters, mercurial alteratives, sarsaparilla, and 

 regulated diet, there was a considerable diminution of the pain and of 

 the swelling of the soft parts, but little or no reduction of the size of the 



