384 Diseases of Bone. 



6. 447. Central Larg-e Round-celled Sarcoma of the Upper 



End of the Femur. — Anterior half of the upper end of the 

 above femur — macerated. 



It shows the destruction of the bone at one spot, and its 

 rarefaction at others. There is a slight amount of new periosteal 

 bone formed beyond the rarefied area, probably " irritative," and 

 due to the tumour's growth. G. C. 3323. 



Presented hy Charles W. Cathcart, F.R.C.S.E. 



6. 448. Central Large Round-celled Sarcoma of the Upper 



End of the Femur. — Macerated fragments of the above 

 tumour, which fell apart when a portion Avas macerated. 



These show that bone was scattered in isolated pieces 

 throughout the tumour substance beyond the femur, 



G. C. 3324. 

 Presented &y Charles W. Cathcart, F.R.C.S.E. 



6. 449. Central Sarcoma of the Tibia.— Part of a tibia — 



macerated, illustrating the above. 



The shaft is partially destroyed at one place, and shows 

 a growth of new periosteal bone at others. 



This is apparently the result of the growth of a tumour 

 similar to the last. Formerly described as " necrosis." 



G. C. 1161. 

 Presented hy Professor James Russell. 



6. 450. Central Sarcoma at the Lower End of the Femur. 



— Section of the lower end of a child's right femur and adjacent 

 part of tibia — in spirit, illustrating the above. 



"Janet S. , aged 9, was ailmitted to the Royal Infirmar)', Edinburgh, 

 on 14th September, suffering from a great swelling of the right knee. 



"The swelling is of a hard, elastic nature, with large superficial 

 veins. The thigh of the same side is a little swelled, but not pained or 

 inflamed. 



