182 APPENDIX III. 



tinctly, and in the cartilage of hip- and knee-joints. 

 The spleen and liver seemed to have less lithium 

 than the vitreous and aqueous humour and the lens. 



Experiment 4. A guinea-pig was given three 

 grains of chloride of lithium, and in twenty-four 

 hours it was killed. Lithium was found in the 

 cartilage of the hip- and knee-joints, in the centre of 

 the lens, in the nails, and in the outer moisture of 

 the eye. 



Experiment 5. To another, the hair of which 

 gave no trace of lithium, were given three grains of 

 chloride of lithium, and it was killed in eight hours ; 

 as usual, lithium was found in all the organs by 

 far the most in the kidneys. Little was found in 

 the blood. It was quite evident in the cartilage of 

 the hip-joint, and very distinct in the outer layer of 

 the crystalline lens, but none at all could be found 

 in the centre of the lens. Both lenses were 

 examined more than six different times with the 

 same result. 



Experiment 6. In a guinea-pig, much younger 

 than the last, which was killed eight hours after 

 three grains of chloride of lithium, the whole lens 

 was penetrated the smallest particle, even one- 

 twentieth the size of a pin's-head, taken from each 

 part of the lens, showing the lithium distinctly. 

 The whole lens of another pig that had taken no 

 lithium was burnt, and did not show the slightest 

 trace of lithium. 



Experiment 7. Another guinea-pig was given 

 three grains of chloride of lithium, and it was killed 

 in four hours. Lithium was found in the fibrin, 



