APPENDIX III. 183 



serum, and corpuscles of the blood, in the cartilage 

 of the hip-joint, and in the lens, even in its most 

 central part. There was scarcely any difference 

 between the inner and outer part. The vitreous 

 and aqueous humours showed much more evidence 

 of lithium than the lens itself did. 



Experiment 8. A guinea-pig, the urine of which 

 gave no trace of lithium, had three grains of chloride 

 of lithium, and was killed in two and a half hours. 

 The lithium was found in the cartilage of the hip- 

 joint distinctly but faintly. The blood showed the 

 lithium very distinctly, much more so than in any 

 of the previous experiments. The outer portion of 

 the lens showed lithium, though but slightly. The 

 inner portions of the lens showed more. The 

 vitreous and aqueous humours showed lithium very 

 distinctly. 



Experiment 9. A large guinea-pig was given 

 three grains of chloride of lithium, and it was killed 

 in an hour. Lithium was found in the blood, urine, 

 and nails very distinctly ; in the cartilage of the 

 hip- and knee-joints very faintly ; in the vitreous 

 and aqueous humours of the eye very distinctly. 

 No lithium was found in the lens, not even when 

 half the lens was taken for a single experiment. 

 The stomach contained food. 



Experiment 10. Another guinea-pig was killed 

 an hour after the same dose. The lithium was 

 found strongly in the blood, bile, liver, and kidney. 

 Traces occurred in the brain and in the cartilage of 

 the hip-joint. It was present distinctly in the 

 humours of the eye and in the lens. The difference 



