APPENDIX III. 185 



the brain. The lens showed no lithium when incin- 

 erated entire, but the aqueous extract of the lens 

 showed minute traces of lithium. 



Experiment 14. An old guinea-pig, also fasting 

 for about thirty-six hours, was given the same 

 quantity of chloride of lithium, and was also killed 

 in half an hour. No lithium could be detected 

 before the dose, in the urine, nor in the toe-nail of 

 one leg. After taking the lithium, the animal was 

 wrapped up in a cloth, the leg only being left out to 

 prevent it from licking the toe ; after death, the 

 nails of this leg showed that some lithium was there. 

 The sciatic nerve showed traces of lithium. The 

 cartilage of the hip-joint, when touched with red- 

 hot wire, showed no lithium, but scrapings from the 

 surface showed traces of lithium. The humours of 

 the eye showed traces of lithium, but the lens 

 showed no lithium even 'in the watery extract. The 

 brain showed only exceedingly faint traces of 

 lithium. The stomach was almost completely 

 empty. 



Experiment 15. A guinea-pig was kept fasting 

 for twenty-four hours ; it was then given three 

 grains of chloride of lithium, and it was killed in a 

 quarter of an hour. Lithium was found in the bile, 

 liver, kidney, and blood, very distinctly ; very 

 faintly in the brain and in the cartilage of the hip- 

 joint, and in the humours of the eye. None was 

 found in the lens. The stomach contained only 

 some water, no solid food. 



Experiment 16. Three fresh guinea-pigs were 

 taken ; one was killed without taking any lithium. 



