188 APPENDIX III, 



red-hot wire. The stomach was about half full 

 of food. 



The old one showed lithium distinctly in the 

 outer part of the lens, but scarcely the faintest trace 

 in the inner part. The cartilage of the hip-joint 

 showed lithium quite as distinctly as the cartilage 

 of the young pig. 



The other two guinea-pigs were kept. After 

 forty-eight hours, the urine of both showed lithium 

 very distinctly in one drop. Six days afterwards, 

 the urine of the young animal still showed lithium 

 faintly in each drop. The urine of the old one 

 found in the bladder after its death showed lithium 

 faintly in each drop. 



Both were killed on the sixth day, and no lithium 

 could be detected in the alcoholic extracts of the 

 kidneys, livers, or lenses of either. 



A short series of experiments were made with the 

 view of determining the rate at which the salts of 

 lithium diffuse into the textures when the lithium 

 is injected into the skin instead of passing through 

 the stomach. 



Three grains of chloride of lithium in solution 

 were injected into the skin of the back of the neck 

 of a guinea-pig, and the animal was killed in 

 twenty-four minutes. 



The urine, bile, kidney, and liver showed lithium 

 very distinctly. The cartilage of the hip-joint 

 showed lithium distinctly when touched with a red- 

 hot wire. The aqueous humour showed lithium 

 very distinctly, but the lens, when washed, showed 

 only a very minute trace of lithium when the 



