192 APPENDIX III. 



a loop of the wire. The aqueous extract of the lens 

 showed only faint traces of lithium. The urine 

 showed lithium very distinctly in a single drop. 



The fourth was killed in seventy-two and a half 

 hours. The lens showed no lithium when the ash 

 was treated with sulphuric acid and alcohol. The 

 ash of the kidney showed no lithium directly, but 

 when treated with sulphuric acid and alcohol, 

 showed traces of lithium. The urine still showed 

 lithium distinctly in one drop. 



The fifth guinea-pig: on the seventh day after 

 the dose, the urine showed lithium in one drop ; 

 ninth day, still faint traces of lithium in the urine 5 

 eleventh day, urine directly shows no lithium, but 

 the ash still shows faint traces ; thirteenth day, ash 

 of urine shows no lithium, but alcoholic extract 

 shows lithium distinctly ; fourteenth day the same ; 

 sixteenth day the same; thirty-sixth day, when 

 killed, no lithium could be detected in the bones, 

 nerves, lens, or vitreous or aqueous humours, nor in 

 the urine, kidney, or liver. 



Experiment 20. Two guinea-pigs, in the urine 

 of which no lithium could be detected, were given 

 each half a grain of chloride of lithium. 



In three hours and fifty minutes afterwards one 

 was killed. The cartilage of the hip -joint showed 

 no lithium when simply touched with a red-hot 

 wire. Scrapings from the surface of the cartilage 

 showed faint traces of lithium. The sciatic nerve, 

 humours of the eye, and the brain showed faint 

 traces. The muscles of the thigh showed the lithium 

 much more distinctly than the sciatic nerve. The 



