196 APPENDIX III. 



extract of the lens. An old guinea-pig in the same 

 time had no lithium in the lens. 



With two grains, a young guinea-pig in six hours 

 had lithium distinctly in all parts of the lens. An 

 old guinea-pig had in the same time scarcely any 

 lithium in the inner part, but some in the outer 

 part of the lens. . 



With the same quantity, in six days neither a 

 young nor an old guinea-pig gave any trace of 

 lithium in the alcoholic extract of the kidney, liver, 

 or lenses. 



When two grains of chloride of lithium were 

 taken, after six hours the lithium was more distinct 

 in the outer than in the inner part of the lens. In 

 twenty-four hours no difference in the different parts 

 of the lens was detectable. In forty-eight hours 

 still no difference was observed. In ninety-six hours 

 (four days) no lithium was detectable in the lens or 

 in a cartilage of a joint; still the urine showed 

 lithium very distinctly even in one drop. 



After one grain of chloride of lithium, in five 

 hours and a half the lithium was more distinct in 

 the outer than in the inner part of the lens. In 

 twenty-four hours and a half there was no difference 

 throughout the lens. In forty-eight hours the 

 watery extract of the lens showed faint traces of 

 lithium. In seventy-two hours and a half (three 

 days) the alcoholic extract of the lens showed no 

 lithium. The urine still showed lithium distinctly 

 in one drop, and continued to do so for seventeen 

 days in the alcoholic extract. 



After a quarter of a grain, in five hours and thirty- 



