APPENDIX III. 197 



five minutes lithium was distinct in the vitreous and 

 aqueous humours, and very faintly in the lens. 

 After sixteen days, the minutest traces of lithium 

 were detected in the lens, the liver, and the kidneys, 

 but no trace could be found in the blood. (This 

 animal had perhaps somehow eaten the minutest 

 quantity of lithia in the food.)* 



After half a grain of chloride of lithium, in three 

 hours and fifty minutes traces of lithium could be 

 found in the lens, and for thirty-seven or thirty-eight 

 days traces of lithium could be found in the urine. 



After three grains of chloride of lithium, in four 

 hours lithium was in the hair of the belly, and for 

 thirty- two days the urine showed lithium very 

 distinctly. The thirty-third day after the lithium 

 the lens was found to contain minute traces of 

 lithium, and after thirty-nine days the lithium was 

 in the alcoholic extract of the urine. 



4. Experiments on the Bate of Passage of Lithium 

 through the Human Body, and into and out of the 

 Crystalline Lens. 



Experiment 1. A man took ten grains of car- 

 bonate of lithia dissolved in water, four hours after 

 his midday food. 



In five minutes no lithium could be detected in 

 the urine. 



* The skin of guinea-pigs throws off lithium, and it col- 

 lects on the hair and nails, so that it is possible for the 

 animal to redose itself with lithium from its own body, and 

 thus to keep lithium passing in and out of the textures much 

 longer than if a single dose only were taken. 



