APPENDIX III. 217 



After three grains, traces were found in the lens 

 for thirty-three days, and for thirty-nine days the 

 smallest quantity could be found in urine. 



The skin of guinea-pigs throws off lithium, and it 

 collects on the hair and nails ; so that it is possible 

 for the animal to redose itself with lithia from its 

 own body, and thus to keep lithia passing in and 

 out of the textures much longer than if a single dose 

 only were taken. 



3. On the Rate of Passage of Solutions of Lithium in 

 and out of the Human Body. 



In ten-grain doses, lithium may be found in the 

 urine in from five to ten minutes, and continue to 

 pass out for six or seven days. 



In five-grain doses it may be in the urine in from 

 ten to twenty minutes, and continue to pass out even 

 for eight days. 



In twenty-grain doses, it may be found in small 

 quantity in the crystalline lens in two and a half 

 hours, and be present in every particle of the lens in 

 three and a half, five, and seven hours ; and no 

 trace of lithium may be detectable in the lens after 

 seven days, when twenty grains of the carbonate of 

 lithia had been taken. 



4. Results of the Examination of Solid and Liquid 

 Food. 



Although almost every kind of vegetable food, 

 and almost every fluid which we drink, contains 

 infinitesimal quantities of lithia, yet rarely, if ever, 



