STRUCTURAL CHANGES DUE TO DAMAGE. 



295 



gone coagulation-necrosis (Fig. 263). When the granular form of 

 coagulation-necrosis is associated with albuminoid and fatty degen- 

 eration the result is a cheese-like mass, and the process is known 

 as cheesy degeneration (p. 274). 



2. Colliquative Necrosis (Fig. 281). This form of necrosis is fol- 

 lowed by an imbibition of fluid, occasioning a disintegration of the 



FIG. 263. 



/ . e 



Edge of a diphtheritic membrane. Section from the human uvula. (Ziegler.) a, normal 

 stratified epithelium ; b, subepithelial fibrous tissue of the mucous membrane ; c, epithe- 

 lium that has undergone coagulation-necrosis. Only remnants of cells remain in the 

 coarse fibrinous meshwork. d, oedematous subepithelial fibrous tissue containing fibrin 

 and leucocytes ; e, bloodvessels; /, haemorrhage ; g, g, groups of the bacteria causing the 

 necrosis. 



tissue-elements, which are broken up into a granular detritus sus- 

 pended in the fluid. 



The foregoing two forms of necrosis may be associated with each 

 other, or one may follow the other. 



The fate of the necrosed tissue depends upon a variety of circum- 

 stances. The presence of dead tissue excites an inflammation in 

 the living tissue surrounding it, and the character of this inflam- 

 mation often determines the fate of the necrosed mass. (See article 

 on inflammation.) The situation of the dead tissue also affects the 

 result. The following examples will serve to illustrate these vari- 

 ations : 



1. ABSORPTION. The necrosed tissue-elements become disin- 

 tegrated, and the debris either dissolved or carried away through 

 the lymphatic channels by the currents of fluid, or through the 



