STRUCTURAL CHANGES DUE TO DAMAGE. 



311 



FIG. 275. 



s#-r : r -<*v. 



feeginning abscess-formation in the kidney. (Faulhaber.) The suppurative inflam- 

 mation is due to secondary infection by bacilli carried to the kidney from a phleg- 

 monous inflammation of the neck, a, a, bacilli in the capsule of a Malpighian body, 

 the necrotic glomerulus of which is seen in the upper half of the figure ; 6, bacilli in 

 the lumen of a convoluted tubule. The epithelial lining of that tubule has been de- 

 stroyed and dissolved ; only three nuclei, almost devoid of chromatin, remaining. The 

 basement-membrane is also partially destroyed, c, beginning abscess-formation in the 

 interstitial tissue between the convoluted tubules. These foci of suppuration are crowded 

 with leucocytes, in some of which the nuclei have become poor in chromatin through 

 the action of the poisons present. Among the leucocytes are a few bacilli, the virulence 

 of which can only be moderate, since comparatively few of the leucocytes are necrotic. 



FIG. 276. 



EK 



Pus from virulent abscess-formation. (Grawitz.) The leucocytes show marked necrotic 

 changes, chromolysis. c, c, well-preserved leucocytes; E. K., connective-tissue cells 

 from the neighboring granulations ; z, similar cells necrosed. 



