STRUCTURAL CHANGES DUE TO DAMAGE. 



319 



nodules of leprosy and glanders, are forms of subacute inflamma- 

 tion which owe their peculiarities to the infections that occasion 

 them. The tubercle, caused by the presence of the tubercle bacil- 



FIG. 282. 



-., 



ft 



Early stage of experimental tuberculosis ; cornea of rabbit. (Schieck.) Five days after 

 inoculation. Rejuvenescence and beginning degeneration in fixed cells of the fibrous 

 tissue, a, karyolysis in a cell affected by a group of tubercle bacillrwithin the cyto- 

 plasm ; b, karyokinetic figure in another cell. 



lus, is the most common of these inflammations and may be taken 

 as a type of the whole group. 



The tubercle bacillus does not always produce the little in- 



FIG. 283. 



*^5 



*V "- w - J5S* r *^ e ^ 



^r^ -.__ 



Early stage of experimental tuberculosis; cornea of rabbit. (Schieck.) Ten days after inocu- 

 lation. Beginning of a tubercle. The " epithelioid " or young connective-tissue cells are 

 masked by the presence of leucocytes with denser nuclei, which have been attracted by 

 the chemotactie (positive chemotaxis) influence of the materials accumulating in the 

 inflamed focus. 



flammatory nodules called "tubercles." It sometimes occasions 

 a suppurative inflammation of sluggish type, forming "cold ab- 

 scesses," or purulent inflammations of mucous membranes. It 



