364 HISTOLOGY OF THE MORBID PROCESSES. 



and possibly joining each other This reticulum is somewhat more 

 pronounced around the bloodvessels which it supports. The cells 

 may be shaken out of this reticulum, if unembedded sections are agi- 

 tated with water (Fig. 327). 



FIG. 327. 

 I 



II 



Sections from lymphosarcomata. (Kaufmann.) I, firmer variety, with a pronounced 

 stroma; from a mediastinal tumor. II, softer variety, with a more delicate stroma; 

 from a tumor of the small intestine, a, capillary bloodvessel. 



This structure closely resembles that of the lymphadenoid tissue 

 found in the normal lymph-nodes, and there is danger of con- 

 founding the growth with a simple or inflammatory hyperplasia of 

 those organs. This danger is enhanced by the fact that these sar- 

 comata frequently find their origin in a lymph-gland or the lymph- 

 adenoid tissue in the mucous membranes. When the enlargement 

 of the gland is the result of hyperplasia the superabundant tissue 

 is confined within the capsule of the gland, which enlarges as its 

 contents increase in amount. There is also a history of some 

 inflammatory process within the lymphatic province to which the 

 gland belongs. Such is not the case when the increase of tissue is 

 due to the development of a tumor. The growth usually pierces 

 the capsule of the gland, and cannot be traced to inflammatory 

 causes. This penetration of the capsule is an evidence of the in- 

 filtrating power of the growth. Like the small round-cell sar- 

 coma, this variety is liable to early and extensive metastases, and 

 is hardly less malignant than that form. 



c. LARGE ROUND-CELL SARCOMA. As the title implies, this 

 tumor is composed of larger cells than those found in the small 

 round-cell sarcomata. The greater size is due to a larger amount 

 of cytoplasm, in which are rather large round or oval vesicular 

 nuclei, usually one in each cell, but not infrequently cells with two 



