28 THE AMERICAN MONTHLY (Jan 
are inoculated as follows: The first tube by the contents 
of two platinum loops ; the second-tube is inoculated from 
the first, using four loops, and the third by six or eight 
loops from the second dilution. The contents of each tube 
is then poured into Petri dishes and placed in a cool place 
until the gelatin is solidified ; it is then placed in an oven 
and kept ata temperature of 22° C. for twenty-four hours. 
At the end of this time the typhoid colonies are seen as 
transparent, filamentous bodies, along side of the coli 
colonies, which are rounded, with well defined edges, Ac- 
cording to the writer, Piorkoski claims to have found the 
typhoid colonies as early as three days after the begin- 
ning of the illness, and he furthermore claims that they 
may be demonstrated in every case. Twenty-six cases 
have been tested, in all of which the results of the test 
were confirmed by the subsequent clinical history.—Mod- 
ern Medicine. 
A NEw PatTHoGentc Moutp.—W. H. Ophuls and H. 
C. Moffitt in the Philadelphia Medical Journal present a 
preliminary report of a new pathogenic mould which was 
formerly described as a protozoon: under the name ccc- 
cidiodes immitis pyogenes. 
The patient from whom the organism was obtained was 
a farm laborer aged nineteen, whose sickness began with a 
chill, eleven weeks before admission to the hospital. 
After a few days the left pleura was tapped and a large 
quantity of clear fluid was removed. The patient hadan 
irregular fever, the temperature at times reaching 104 ° 
F. The Diazo reaction was present, but not the Widal. 
About four weeks after the onset of his trouble, painful 
inflammation of the knees, elbows, wrists and ankles de- 
veloped. later, there was a fluctuating swelling over 
the left eye, and a large gland developed in the supra- 
clavicular fossa, There was cough, with muco-purulent 
and occasionally bloodstained sputum. There were no 
tubercle bacilli in the sputum. The lungs were irregu- 
