1901] MICROSCOPICAL JOURNAL. 143 
place and a true ring is formed. The Peripheral circula- 
tion in this disease contains very few parasites. 
Filaria and by this term we mean a long slender worm- 
like body existing and swimming in the blood and lym- 
phatics. The ‘‘Filaria sanguinis Hominis” occurs in three 
forms. First, the ‘“‘Filaria Diurna” or that species exist- 
ing by day. Second, the “Filaria Nocturna” or that which 
exists by night, and third, the “Filaria Perstans” or that 
one existing persistently at alltimes. The “Filaria Diurna” 
and the “Filaria Perstans” are confined to patients found 
on the west coast of Africa and adjoining districts, while 
the “Filaria Nocturna” is pandemic in the tropics, and 
‘endemic in certain sections of the United States. The 
Filaria Perstans has been practically proven to be the 
cause of the so-called fatal ‘“‘sleeping sickness’ of the 
Congo region. 
Prognosisas determined by a blood examination in pneu- 
monia shows in this disease as favorable if Leucocytosis 
is present, but is a bad sign if absent even in the mild 
cases and certainly points toward a fatal issue. Leuco- 
cytosis simply shows that the system is re-acting. 
In diphtheria here again, the absence of Leucocytosis 
is a bad sign even in the mildest case. The phenomena 
should keep pace with the severity of the disease. The 
staining reaction is said to be proportional to the severi- 
ty of the disease. Also, in scarlet fever and Scarlatinal 
nephritis, ‘“Hosinophile”’ is the good sign and its absence 
‘abadone. As in the before mentioned, the Leucocytosis 
is proportional to the severity. The foregoing facts simply 
serve to show that a conservative prognosis should not be 
made without a thorough blood examination. 
The blood corpuscle first makes itself known in the 
marrow of long bones from whence it passes into those 
long narrow cylinders the blood vessels, where it must 
meet its foes, must fight disease, be overcome or return 
victorious. 
