On the Formation of Cells in Animal Bodies. 141 



uniformly throughout their entire bulk, but globules of a definite 

 size are emitted, as many as the mass will yield. 



The crystalline lens of many young animals affords, when treated 

 with water, a beautiful illustration of this fact. Its homogeneous 

 material is transformed, under the influence of imbibition, into a 

 vast number of globules of nearly equal size. 



Hyaline embryonic tissues display, under similar conditions, 

 the same phenomenon. 



Certain inferences lead one to suspect that this size-limiting 

 property is due to the crystallizing propensity of some ingredient 

 of these viscid substances. 



Blood-corpuscles (human blood-corpuscles at least) are evidently 

 tiny lumps of a uniformly viscid material. 



When broken up into fragments, each fragment assumes the 

 spherical shape. 



On slow imbibition, they often emit a clear sphere, or a segment 

 of one. 



In various specimens of foetal blood, each blood-corpuscle was 

 seen to emit as many as two or even three equal-sized globules, 

 the original corpuscle being at last no longer distinguishable from its 

 descendants. This is sufficient proof of the uniformly viscous nature 

 of the blood-corpuscles. 



In many cancers the most recently formed part consists of mere 

 fibres. These after a time become " nucleated." The " nuclei " 

 are at first very elongated, this being due to the lateral pressure of 

 the still fibrous texture. But as the mass gradually softens, the ovals 

 expand more and more into spheres, forming the primary globules, 

 round which, as has already been shown, a secondary globule is often 

 seen to shape itself. 



Chemical differentiation transforms first one portion of the fibrous 

 mass into viscid material. This at once strives, by imbibition, to 

 assume the globular shape. The remaining portion may or may not 

 ultimately undergo similar transformation. 



Inflamed serous membranes become often densely "nucleated." 

 In the deeper layers, the "nuclei" are very elongated. At the 

 surface they are perfectly globular, and are detached as minute 

 opaque balls. These balls are the granulation- or the pus-corpus- 

 cles. On imbibition, ojie portion of their soit material swells out, 

 encompassing the rest, which, when forming a single uniform globule, 

 goes under the name of granulation-corpuscle — when, on the other 

 hand, broken up into several granules, constitutes the famous 

 pus-" cell." This is an example of a second mode of "cell "-for- 

 mation. Here the secondary globule is shaped from a portion 

 of the primary mass. 



In some instances these "nuclei" or balls will, when still 

 enclosed within the surrounding texture, undergo the above-men- 

 tioned change on imbibition ; and thus whole rows of granulation - 

 or pus-corpuscles are seen to form. 



This second mode of "cell "-formation is still more strikingly 

 manifested in epithelial textures. In the mucous membrane of the 



