1899] MICROSCOPICAL JOURNAL. 109 



The second slide furnishes an illnstration of "twin- 

 ning" of the tertian parasite — a process not at all un- 

 common in tertian malaria, but much more common in 

 the aestivo-autumnal form. The blood was taken about 

 two hours before the expected chill, from a man suffer- 

 ing from quotidian paroxysms, and the specimen showed 

 a segmenting body and a half-grown parasite in the same 

 red cell. 



The third slide shows another form of twinning of the 

 tertian parasite, which has been seen only in the Cuban 

 cases. In this specimen there were a great many cells 

 containing parasites in which, evidently, the amoeboid 

 motion had been very active, and the parasites, instead 

 of being in a more or less spheroidal form, were strung 

 out into a number of fine threads with nodal thicken- 

 ings. 'In each cell presenting this peculiar appearance 

 there were two achromatic nuclear spots, indicating the 

 presence of two parasites. 



On the fourth slide was a very richly pigmented leuco- 

 cyte of enormous size — one of very many seen in a fatal 

 case of mixed aestivo-autumnal and tertian infection. 

 The importance of these leucocytes was very great in di- 

 agnosis, and their appearance, when typical, seemed to 

 him to be quite as characteristic as that of the para- 

 site itself. ~N. Y. Med. Jour. 



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