SOUTH AFKICAN HORSE SICKNESS 57 



are usually evident about the tenth day, and death takes place about 

 ten or fourteen days after infection, and in the dikkop variety a day or 

 two later. 



"In 1898 I tried inter-tracheal injections of iodine on a case of the 

 dikkop variety, and in twenty-four hours I was so much surprised at the 

 improvement which took place that I decided to give this treatment a 

 further test, and try if possible to perhaps improve on the iodine solution, 

 which I found to give me the only satisfactory results. 



"The inter-tracheal injections used were as follows: 



R. 



Iodine, grs. iv. 

 Pot. lod. grs. xii. 

 01. Terebinth, m. xv 

 Glycerine, 3 . 

 Aqua, boiled, 3 . 



R. 



Iodine, grs. iv. 

 Pot. lod. grs. xii. 

 A. Carbolic, m. xv. 

 Glycerine, 3 ss. 

 Aqua, boiled, 3i. 



Injected once or twice daily. 



" Of thirty-six animals treated in this way seven recovered, twenty-three 

 died within twenty-four hours, and six died in from two to six days 

 from date of admission. 



" In some cases this treatment caused the animal undue disturbance, 

 and coughing for about an hour after the injection; also, if given every 

 twelve hours for two or three days the urine became blood-stained, and 

 on post-mortem examination the kidneys were much enlarged, congested, 

 a livid blue colour on surface, and capsule, if anything, more easily de- 

 tached than normal. 



" The following season I used intravenous injections, which gave more 

 satisfactory results, besides causing practically no disturbance to the 

 animal, so discontinued the inter-tracheal injections. 



" R as follows: 



Iodine, grs. iv. 

 Pot. Iodide, grs. xv. 

 Glycerine. 

 Aqua, boiled, 3i. 



" A noteworthy feature of this treatment is the immediate effect it has 

 on the temperature. 



" In the majority of cases the temperature drops from one or two degrees 

 within twenty-four hours after the first injection, and a gradual decrease 

 of temperature afterwards is a favourable sign; also, the ecchymosis on 

 the conjunctiva is much improved in twenty -four hours. 



" If the disease is discovered the first or second day of the fever, two 



