660 TRYPANOSQMIASIS 



other Europeans and in several natives in the Gambia region, 

 whilst about the same time Manson reported a case of the same 

 kind in the wife of a missionary on the Congo. It thus came 

 to be recognised that in man there occurred a disease having 

 characters somewhat resembling nagana and in which trypano- 

 somes could be demonstrated in the blood, and this was usually 

 referred to as human trypanosomiasis, or trypanosoma fever, 

 the trypanosome being named the Tr. gambiense. 



FIG. 189. Trypanosoma gambiense from blood of guinea-pig, x 1000. 

 See also Plate VI., Fig. 25. 



^Relation of Trypanosomes to Sleeping Sickness. Several 

 views as to the etiology of this disease had been advanced, and 

 the seriousness of the epidemic in Uganda led the Royal Society 

 of London in 1902, at the instigation of the Foreign Office, to 

 dispatch a Commission to investigate the condition on the spot. 

 Soon after its commencing work, Castellani found in some cases in 

 the cerebro-spinal fluid, especially when this was centrifugalised, 

 living trypanosomes resembling the Tr. gambiense ; he also found 

 in 80 per cent, of the cases post mortem a coccus previously 



