688 PHLEBOTOMUS FEVER 



bearing on the pathology of a group of similar affections 

 occurring in various parts of the world, chiefly in coastal areas, 

 and going under a variety of names. Examples are dengue, 

 the three-day fever of various regions, Canary fever, Shanghai 

 fever, Chitral fever, and the seven-day fever or simple continued 

 fever of India. Of these, that presenting the most definite 

 clinical picture is dengue, a condition for long well known and 

 having an extensive distribution, and it may be said that Ash- 

 burn and Craig in the Philippines found the blood in dengue 

 as in pappataci to be infective even after nitration. Whether 

 all these disease conditions are identical further research must 

 decide; at present Birt believes that at any rate pappataci 

 and dengue are distinct, and certainly Doerr does not in his 

 description allude to the terminal skin eruption which Manson 

 believes to be of very constant occurrence in the latter. The 

 rarity of a fatal result in these diseases makes their investigation 

 by inoculation of the human subject relatively safe. 



