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MANUAL OF BACTERIOLOGY. 



The following is a list of the most important diseases of man 

 caused by bacteria. The proof as required by the rules of 

 Koch is not complete for all of them: 



Tuberculosis, 

 Leprosy, 

 Glanders, 

 Anthrax, 

 Tetanus, 



Malignant edema, 

 Bubonic plague, 

 Malta fever, 

 Erysipelas, 



Suppuration and 

 certain inflamma- 

 tory conditions al- 

 lied to it, 



Epidemic cerebro- 

 spinal meningitis, 



Gonorrhea, 



Chancroid or soft 

 chancre, 



Lobar pneumonia, 



Influenza, 

 Diphtheria, 

 Typhoid fever, 

 Dysentery (not 

 amebic dysen- 

 tery), 



Asiatic cholera, 

 Relapsing fever, 

 Actinomycosis. 

 Syphilis (probably) . 



Malaria and amebic dysentery are caused by microscopic 

 unicellular animal organisms (protozoa). It has been claimed 

 that small-pox is caused by protozoa; this view has acquired 

 added interest from the recent researches of Councilman. 

 Recent work indicates that the "sleeping sickness" (of Africa) 

 and some other diseases of tropical climates are caused by 

 protozoa (see appendix). 



Thrush and certain parasitic skin diseases are caused by 

 fungi of more highly organized structure than bacteria. 



In each of the following diseases there is good reason to 

 think that the cause is some kind of microorganism, but it has 

 not yet been discovered : 



Chicken-pox, measles, scarlet fever, German measles, mumps, 

 whooping-cough,* yellow fever, typhus fever, rabies, dengue. 



Rheumatic fever and beri-beri would be placed in this list 



by many writers. 







*Bordet and Genou* have isolated an organism in whooping-cough from spu- 

 tum by the use of a mixture of rabbit's blood with agar and a small amount of 

 glycerin extract of potato. They state that another organism resembling the 

 influenza bacillus often presents a serious obstacle to the isolation of the real 

 whooping-cough bacillus. Ann. del' lust. Past. XXI., No. 9, Sept. 25, 1907. 

 PP- 7 2 7-732. 



