4 22 MANUAL OF BACTERIOLOGY. 



Melaniferous leukocytes are seen in the blood, being espe- 

 cially abundant after the paroxysm in all forms of malarial 

 infection.* These are phagocytes which have taken up the 

 pigment granules liberated by the disintegration of the 

 erythrocytes. 



Small-pox and Vaccinia. Micrococci of various sort 

 have been found in the pustules of small-pox and vaccinia, 





* 



" * 



FIG. no. Trypanosomes in the blood of the rat. Romanowsky stain. 

 (X 1000.) 



but indicate only a secondary infection. Other microorgan- 

 isms have been described. The most important are certain 

 bodies often considered protozoa. In both small-box and 

 vaccinia small, round homogeneous bodies, 2 to 4 /* in diam- 

 eter, have been found in the epithelial cells of the vesicles. 

 Inoculation of vaccine lymph into the rabbit's cornea leads to 

 the production of similar bodies in the epithelial cells of the 



*See also Ewing. Journal Experimental Medicine. Vols. V. and VI. 



