2O2 BACTERIOLOGY. 



in endocarditis ulcerosa ; as chains also in the muscle 

 of the heart, and forming plugs in the vessels of 

 the heart, spleen, and kidney. Some forms are 

 identical with Staphylococcus pyogenes aureus* 

 Micrococci have also been described in connection 

 with chronic and other forms of endocarditis. 



Streptococcus in diphtheria. Oval cocci, 

 35 to ri n in diameter, have been described as 

 characteristic of diphtheria. t The cells lie singly, 

 in pairs or in rosaries, and in spherical or cylin- 

 drical masses in diphtheritic membranes and the 

 surrounding connective and muscular tissues. 

 From the point of infection they can be traced 

 along the lymphatics, and are found in the blood, 

 heart, liver, kidneys, and other organs. In severe 

 cases the blood capillaries and uriniferous tubules 

 are blocked up. 



The attempt to get pure cultivations in nutrient 

 media and to make inoculation experiments has 

 not yet succeeded ; a bacterium has also been 

 described as associated with diphtheria (p. 230). 



Streptococcus articulorum, Loffler. Cocci 

 forming remarkably long chains. Cultivated in 

 nutrient gelatine they form pale-grey watery- 

 looking droplets. They frequently produce a 

 fatal result when inoculated in mice, and the 

 chains are found in the spleen and other organs. 

 Rabbits inoculated subcutaneously in the ear 



* Ziegler, Patholog. Anatomy. 1885. 



t Oertel, Deutches A rchiv f. Klin. Me#. 1871. 



