SYSTEMATIC AND DESCRIPTIVE. 237 



to be intimately associated with croupous pneu- 

 monia, but any exact relation cannot be considered 

 as established. The organism differs from the so- 

 called Bacterium pneumonia crouposce in that it is 

 pathogenic in rabbits, it can be directly isolated 

 from rusty sputum, and it requires a temperature 

 for its growth at which nutrient gelatine is liquefied. 

 The cocci were first observed in the blood of a 

 rabbit inoculated with healthy saliva, and again 

 found in a rabbit which died after inoculation with 

 the saliva of a child suffering from rabies. Later 

 they were isolated from the blood of rabbits in- 

 oculated with the buccal secretions of different 

 individuals, and were found to be constantly 

 present in the rusty sputum of pneumonic patients. 



Bacterium crassum sputigenum, Kreibohm. 

 Short thick rods with rounded ends. Colonies 

 on plate-cultivations appear as clear grey-white 

 points, which ultimately form greyish slimy drops. 

 In test-tubes they develop very quickly a nail- 

 shaped growth. They are fatal to mice, and after 

 death are found in the blood, and in sections, more 

 especially in the capillaries of the liver. Rabbits 

 die of septicaemia after intravenous injection. A 

 large quantity of a cultivation injected into the cir- 

 culation sets up fatal gastro-enteritis in rabbits and 

 dogs in 3 10 hours. They were isolated from 

 sputum 



Bacterium pneumonicum agile (Bacillus 

 pneumonicus agilis, Schou.). Short thick rods, or 



