27O BACTERIOLOGY. 



Bacillus malariae, Klebs (Bacillus in inter- 

 mittent fever}. Rods, 2 7 /x long, which grow 

 into twisted threads. Spore-formation takes place 

 in the centre, or at either end (Plate I., Fig. 14). 



Inoculated in rabbits they were stated to produce 

 a febrile disorder analogous to malarial fever,* 

 and in the spleen and marrow the threads and 

 spores of the bacilli were found in abundance. 

 Bacilli with end-spores have been discovered also 

 in the blood of patients suffering from malaria. t 



The bacilli were first described as present in the 

 soil of the Roman Campagna. 



According to more recent observations, peculiar 

 amoeboid bodies and motile filaments are constantly 

 present in the blood of cases of malaria. These 

 organisms, or plasmodia malaria, appear to be closely 

 allied to the flagellated protozoa (see Appendix B). 



Bacillus of choleraic diarrhoea from meat- 

 poisoning, Klein. J Rods from 3 9 //, in length, 

 1*3 ft wide, rounded at their extremities, singly 

 or in chains of two. Spore-formation occurs, the 

 spores being i /* thick, oval, and situated in the 

 centre or at the end of the rod. 



Feeding with the bacilli and inoculation produced 

 positive results. At the autopsy, pneumonia, peri- 

 tonitis, pleuritis, enlargement of the liver and spleen, 

 and haemorrhage were observed, and bacilli were 



* Klebs and Tommasi Crudeli, A rchiv. f. Experimental Pathol. 

 1879. 



t Marchiafava, ibid. 

 \ Klein, p. 87. 



