SYSTEMATIC AND DESCRIPTIVE. 335 



In the slimy detritus the little pale-yellow grains 

 of fungus can be detected. In cattle the lower 

 jaw is usually affected, and then the upper jaw 

 and neighbouring parts. The organism may also 

 occur in nodular tumours in the lung, subcutaneous 

 and intermuscular tissues. It is the cause of 

 " wooden tongue," and also of diseases which have 

 been variously described before their true nature 

 was understood as bone-canker, bone-tubercle, 

 osteo-sarcoma, etc. 



In man the pulmonary formations tend to 

 break down early, forming fistulse and sinuses, 

 with the clinical character of empyema. In one 

 case there were the symptoms of chronic bronchitis 

 with foetid expectoration. In other cases the dis- 

 ease, originating in the lung, spread to the prse- 

 vertebral tissues. If the actinomyces invade bones, 

 as has been especially observed in the bodies of the 

 vertebrae, caries results. In another group of cases 

 the organism has been said to produce disease of 

 the intestinal canal. The fungus has also been 

 detected in the crypts of the tonsils of healthy pigs, 

 and a similar, if not identical, one in the sper- 

 matic duct of the horse.* 



The disease has been transmitted from cattle to 

 cattle by inoculation,! and a rabbit has been in- 

 fected by means of a piece of actinomycitic tumour 



* Johne, Bericht tibr das Veterindrwesen im Konigreich 

 Sachsenfurdasja.hr. 1884. 

 t Johne, Deutsche Zeitschr. /. Thiermedicin . 1881, 



